Cresswell has missed the last four matches due to groin and Achilles injuries, while Evans has been sidelined for three games with a knee problem.
Irish midfielder David McAllister, who scored on his full debut in last Saturday's 3-2 home win over Bristol City, is also hoping to return to Micky Adams' starting line-up after missing Monday's victory at Reading due to a calf strain.
Teenage centre-half Harry Maguire will return to contention following a one-game ban and Adams must decide whether to put him straight back into his side.
Forward Daniel Bogdanovic is unlikely to feature as he is struggling with illness as well as an ankle knock.
The Blades require a third successive win in the hope that Doncaster lose at home to Leicester in order to keep their faint survival hopes alive.
Barnsley striker Marlon Harewood is a major doubt.
Harewood, on loan from Blackpool, sustained a hamstring injury in last Saturday's defeat at Watford and missed Monday's home draw with Doncaster.
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Sheffield United - Barnsley Live Streaming
14:00 +00:00, April 30, 2011
Bramall Lane, England
Watch Sheffield United vs Barnsley live
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